11/20/2023 0 Comments Sneak peek test resultsReal-time quantitative PCR was utilized to detect male fetal DNA using a multi-copy sequence on the Y chromosome and total cell-free DNA using an autosomal control target gene. Using a commercial DNA isolation kit, circulating cell-free DNA (ccfDNA) was extracted from the maternal plasma samples. Maternal plasma was separated from whole blood via centrifugation. Three to four milliliters (mL) of maternal blood were drawn from each participant via venipuncture at three gestational ages (i.e., 6, 7, and 8 -10 weeks’ gestation). After excluding participants that reported miscarriage during the study, reported twin/triplet pregnancy, or miscalculated gestational age at the time of the initialsample collection, 115 individuals completed the trial in its entirety. Method: Between May and September 2021, 156 pregnant women were recruited from 12 clinics in the United States. The SneakPeek assay was further optimized to enable fetal sex identification at earlier gestations and its performance characteristics were determined at 6-weeks’ gestation. To our knowledge, no prior study has shown fetal sex identification from maternal plasma earlier than seven weeks of gestation with high accuracy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Ĭlinics Mother Child Health, Vol.19 Iss.4 No:1000419 ABSTRACTīackground: The SneakPeek® Early Gender Test was previously shown to be 99.9% accurate in determining fetal sex as early as seven weeks of gestation. CMCH-22-17127 (R) Published: 0, DOI: 10.35248/2090-7214.22.19.419Ĭitation: Szucs HD, Asprer L, Abunadi N, Milot H, Cacia S, Jacob C (2022)SneakPeek Early Gender Test: The Earliest and Most Accurate Method for Fetal Sex Determination at 6-Weeks Gestation. CMCH-22-17127 Editor assigned: 1, PreQC No. Gateway Genomics, San Diego, California, USAĬorrespondence to: Henriett Diana Szucs, Gateway Genomics, San Diego, California, US, E-mail: 0, Manuscript No. Henriett Diana Szucs*, Lia Asprer, Nora Abunadi, Haley Milot, Sarah Cacia, Chris Jacob
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